Evidence map›Paper›PMID 40488120›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2025

N-acetyl-L-cysteine improves mitochondrial and oxidative defects in the acadian variant of fanconi syndrome.

Inas Al-Younis, Rebeca Martín-Jiménez, Mehtab Khan, Yann Baussan, Caroline Jose, Yves Thibeault, Etienne Hebert-Chatelain

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inas Al-YounisCanada Research Chair in Mitochondrial Signaling and Physiopathology, Moncton, NB, Canada.
Rebeca Martín-JiménezCanada Research Chair in Mitochondrial Signaling and Physiopathology, Moncton, NB, Canada.
Mehtab KhanCanada Research Chair in Mitochondrial Signaling and Physiopathology, Moncton, NB, Canada.
Yann BaussanCanada Research Chair in Mitochondrial Signaling and Physiopathology, Moncton, NB, Canada.
Caroline JoseVitalité Health Network, Moncton, NB, Canada.
Yves ThibeaultDepartment of Nephrology, G.-L.-Dumont University Hospital Center, Moncton, NB, Canada.
Etienne Hebert-ChatelainCanada Research Chair in Mitochondrial Signaling and Physiopathology, Moncton, NB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Acadian variant of Fanconi Syndrome (AVFS) is a rare genetic disorder characterized by renal deficiencies. AVFS is caused by a mutation to

Indexed as

AcetylcysteineAntioxidantsFanconi SyndromeMitochondriaOxidative StressCell RespirationCells, CulturedElectron Transport Complex IFibroblastsHumansMalondialdehydeMembrane Potential, MitochondrialAcetylcysteineAntioxidantsElectron Transport Complex IMalondialdehydeantioxidantkidney diseasemitochondrial diseaseoxidative stressrare disease

Identifiers

PMID40488120
PMCPMC12142771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.