Evidence map›Paper›PMID 40488119›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Thinning Choroidal Thickness and Flattening Morphology of Higher Myopia Eyes in Chinese Adults with Anisometropic Myopia: A Comparative Study.

Zhirong Zhang, Yongle Bao, Jian Cao, Yong Ma, Yanze Yu, Zhanying Wang, Jiayi Hu, Fang Liu, Yuhao Ye, Xingtao Zhou and 1 more

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhirong Zhang *Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Yongle Bao *Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Jian Cao *Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Yong MaDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Yanze YuDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Zhanying WangDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Jiayi HuDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Fang LiuDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Yuhao YeDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.
Xingtao ZhouDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.ORCID 0000-0002-3465-1579
Jing ZhaoDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate variations in choroidal thickness and morphology in the eyes of Chinese adults with anisometropic myopia and their relationship with myopia. Methods: This study included 107 adults (aged 17-50 years) with myopia and normal visual acuity. Based on interocular differences in spherical equivalent (SE), participants were categorized into an anisometropia group (≥ 1 diopter, [D], N = 33) and a control group (< 1D, N = 74). Optical coherence tomography was used to measure ocular biometry and choroidal thickness at seven horizontal regions, extending from nasal (N) to temporal (T). These regions included the subfoveal region, 0.5 mm (T/N0.5), 1.5 mm (T/N1.5), and 2.5 mm (T/N2.5) from the subfoveal. A proposed fitting curve equation described the choroidal curvature. Results: Binocular choroidal thickness exhibited a decreasing trend from temporal to nasal regions, with slight thickening in the subfoveal region compared to choroidal thickness at T0.5 and N0.5 in both groups ( Conclusion: In adults with myopia, choroidal thickness shows a decreasing trend from temporal to nasal region and is negatively correlated with myopia degree. Morphological flattening in anisometropic eyes suggests choroid remodeling for axial adaptation elongation.

Indexed as

anisometropiachoroidal curvaturechoroidal thicknessrefractive error

Identifiers

PMID40488119
PMCPMC12141424

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.