Effect of Introducing Leucine Residues into 2‑Aminoisobutyric Acid-Based Amphiphilic Helical Peptides on Intermolecular Interactions and Peptide Self-Assembly.

Kasumi Yamaguchi, Tomoichiro Kusumoto, Takeshi Araki, Yuki Gomibuchi, Takuo Yasunaga, Satoshi Osada, Junichi Taira

Abstract read

In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kasumi YamaguchiDepartment of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Saga 840-8502, Japan.

Tomoichiro KusumotoDepartment of Bioscience and Bioinformatics, Fukuoka 820-8502, Japan.

Takeshi ArakiDepartment of Bioscience and Bioinformatics, Fukuoka 820-8502, Japan.

Yuki GomibuchiDepartment of Physics and Information Technology, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan.

Takuo YasunagaDepartment of Physics and Information Technology, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan.

Satoshi OsadaDepartment of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Saga 840-8502, Japan.ORCID https://orcid.org/0000-0002-3988-1322

Junichi TairaDepartment of Bioscience and Bioinformatics, Fukuoka 820-8502, Japan.ORCID https://orcid.org/0000-0002-8438-865X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, self-assembling de novo-designed peptides have attracted increasing attention as materials for constructing submicrometer-scale structures. We have previously conducted structure-activity relationship studies on the BXBA-20 series of 20-residue amphiphilic peptides containing 2-aminoisobutyric acid (Aib) [Higashimoto, Y. et al. (1999)

Identifiers

PMID40488101

DOI10.1021/acsomega.5c02490

PMCPMC12138716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.