Evidence map›Paper›PMID 40488083›Full record

ArticleACS omega2025

Triazolinedione Modification of Prenylated Peptides, Proteins, and DNA: Toward a Single-Site Multilabeling Approach for Biomolecules.

Laure Tack, Alex Manicardi, Grazyna Leszczynska, Agnieszka Dziergowska, Alyssa Ghielmetti, Kamil Unal, Klaas Decoene, Johan Winne, Annemieke Madder

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laure TackDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.
Alex ManicardiDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.ORCID https://orcid.org/0000-0003-0083-1392
Grazyna LeszczynskaInstitute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz,Poland.
Agnieszka DziergowskaInstitute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz,Poland.
Alyssa GhielmettiDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.
Kamil UnalDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.
Klaas DecoeneDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.
Johan WinneDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.ORCID https://orcid.org/0000-0002-9015-4497
Annemieke MadderDepartment of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent, Belgium.ORCID https://orcid.org/0000-0003-0179-7608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In efforts to shed light on the complexity of biological processes, attaching several or different payloads onto a biomolecular target of interest has become an interesting tool within the field of bioconjugation. Herein, we report on the exploitation of prenylated (bio)-molecules in a 1,2,4-triazole-3,5-(4

Identifiers

PMID40488083
PMCPMC12138590

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.