Evidence map›Paper›PMID 40488045›Full record

ReviewACS omega2025

Removal of Tobacco Specific Carcinogenic Nitrosamines in Mainstream Cigarette Smoke and Aqueous SolutionA Review.

Katlego Z Setshedi, Arjun Maity, Atlegang Nyakale, Sebasa Ramahlare, Vongani P Chauke, Thulisile Nkomzwayo, Vusani Mandiwana, Suprakas Sinha Ray, Lerato Hlekelele

Abstract readReview
In one paragraph

Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katlego Z SetshediCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Arjun MaityCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID https://orcid.org/0000-0002-8057-5749
Atlegang NyakaleCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Sebasa RamahlareCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Vongani P ChaukeCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Thulisile NkomzwayoAdvanced Agriculture, Food and Health Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Vusani MandiwanaCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.
Suprakas Sinha RayCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID https://orcid.org/0000-0002-0007-2595
Lerato HlekeleleCentre for Nanostructure and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tobacco-specific N-nitrosamines (TSNAs), which are associated with several cancers, are formed during the processing of tobacco alkaloids. Since tobacco smoking poses serious health risks, scientists, governments, and health regulators globally have denounced it and categorized its constituents according to their carcinogenicity. Tobacco smoke investigations are guided by standardized methods (ISO). With the help of standardized smoke-generating machines, precise quantification of TSNAs and other smoke constituents is now possible thanks to advancements in analytical techniques. This information supports initiatives to reduce the amount of TSNAs that smoking exposes people to. This review covers the occurrence, formation pathways, precursors, and control strategies through removal technologies, providing thorough analysis of the state of science today regarding TSNAs. The adsorption characteristics of different materials as possible filter additives or modifiers are critically discussed, emphasizing important elements like porosity, layering, acidity/alkalinity, and surface area that affect their performance for capturing TSNAs from smoke. While scientific understanding of these areas is still evolving, this review intends to provide for the first time research progress on the adsorption properties of various materials, including zeolites, silica, few-layer black phosphorus, metal-organic frameworks, and molecularly imprinted polymers, among others, for reducing TSNAs present in both cigarette smoke and aqueous solutions.

Identifiers

PMID40488045
PMCPMC12138646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.