ArticleWorld journal of gastrointestinal oncology2025
Natural killer cell dysfunction is associated with colorectal cancer with severe COVID-19.
Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSevere acute respiratory syndrome coronavirus 2 induced coronavirus disease 2019 (COVID-19) has posed a great challenge to public health worldwide and also increased susceptibility to colorectal cancer (CRC). Natural killer (NK) cells serve as the first line of defense in the host's innate immune system, performing natural killing functions and mediating cytotoxicity against tumors and viruses. Therefore, a better understanding of NK cell cytotoxicity may facilitate the development of treatment strategies for CRC-associated with COVID-19.
aimTo investigate the cytotoxic killing function of peripheral NK cells in patients with CRC and severe COVID-19 (CRC
methodsThe percentages of circulating NK and NKT cells in CRC
resultsThe numbers and percentage of peripheral NK and NKT cells in patients with CRC
conclusionCRC
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