ArticleRegenerative therapy2025
Historical evolution, hotspots, and trends in tendon tissue engineering: A bibliometric analysis.
Article in Regenerative therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Nanofiber based transformative approaches for tendon regenerative engineering: past, present and future.Nanomedicine (London, England) · 2026Review
- Immortalized Rat Tendon-Derived Stem Cells for Tendon Tissue Engineering.Bioengineering (Basel, Switzerland) · 2026Article
- Salvia miltiorrhiza (Danshen) promotes Achilles tendon repair: from network pharmacology prediction to in vivo mechanistic validation.Frontiers in pharmacology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical evolution, research hotspots, and future trends to reveal core research directions and potential pathways. Methods: Based on literature from WoS CC (1991-2024) and analyzed using VOSviewer, CiteSpace, and Bibliometrix, the study evaluates publication trends and research patterns. Results: Findings show continuous growth in annual publications. The United States and China are key contributors with close collaboration. Chang James is the most prolific author, and stable research teams have emerged, though inter-team cooperation remains limited. Acta Biomaterialia publishes the most papers in this field, characterized by interdisciplinary integration. Key research focuses include scaffolds, seed cells, and rotator cuff injuries. Frontiers involve ideal scaffold construction, tendon adhesion prevention, and regeneration strategies. Future directions emphasize novel biomaterials, tendon-bone interface healing, innovative seed cell cultivation, tendon growth microenvironment construction, and clinical translation of research outcomes. Conclusion: This bibliometric analysis reveals the core research directions and potential pathways in tendon tissue engineering, providing a reference for future studies.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.