Evidence map›Paper›PMID 40487879›Full record

ArticleThe World Allergy Organization journal2025

Using mobile technology to increase adherence to sublingual immunotherapy: Real-world study with a new app/web platform AllergyVax®.

Matheus Fonseca Aarestrup, Akinori Cardozo Nagato, Paula Fonseca Aarestrup, Edir Paula Cheloni, Beatriz Julião V Aarestrup, José Otávio Amaral Correa, Fernando Monteiro Aarestrup

Abstract read
In one paragraph

Article in The World Allergy Organization journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matheus Fonseca AarestrupAllergy and Immunology Department - Hospital Maternidade Therezinha de Jesus - HMTJ, Juiz de Fora, MG, Brazil.
Akinori Cardozo NagatoPhysiology Department, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
Paula Fonseca AarestrupHospital Israelita Albert Einstein, São Paulo, Brazil.
Edir Paula CheloniPediatrics Department - Hospital Maternidade Therezinha de Jesus - HMTJ, Juiz de Fora, MG, Brazil.
Beatriz Julião V AarestrupMorphology Department, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
José Otávio Amaral CorreaDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, MG, Brazil.
Fernando Monteiro AarestrupAllergy and Immunology Department - Hospital Maternidade Therezinha de Jesus - HMTJ, Juiz de Fora, MG, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen immunotherapy (AIT) is a key therapeutic approach for allergic rhinitis and asthma, demonstrating the ability to modify disease progression by targeting type 2 inflammation. This study evaluates the efficacy of a mobile application (app/web platform) AllergyVax®, designed to implement a patient-centered care (PCC) strategy to increase patient engagement in the treatment. A retrospective cross-sectional analysis was conducted with 482 patients diagnosed with respiratory allergic diseases who initiated sublingual immunotherapy (SLIT). Participants were divided into 2 groups: Group A received standard information, while Group B utilized the AllergyVax® app for managing treatment. This app provided daily reminders, evaluated symptom control through standardized questionnaires, and facilitated communication between patients and healthcare providers. Results indicated a significant increase in adherence rates among app users, with 92.11% adhering to SLIT compared to 46.32% in the non-app group. The app users exhibited a 2.42 times greater likelihood of maintaining adherence and reduced dropout rates by 82%. The AllergyVax® app improved adherence across all demographics, emphasizing the importance of innovative digital tools in enhancing patient engagement and treatment outcomes. In conclusion, this study highlights the critical role of mobile technology in promoting adherence to SLIT, suggesting that integrating digital solutions into AIT can lead to better management of allergic diseases and improved patient outcomes.

Indexed as

AdherenceAllergen immunotherapyAppSLITTechnologyWeb

Identifiers

PMID40487879
PMCPMC12141892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.