Evidence map›Paper›PMID 40487818›Full record

ArticleIDCases2025

Intraparenchymal hemorrhage from infective endocarditis: A case of double trouble.

Farhan Khalid, Anosh Aslam Khan, Hardikkumar Bhanderi, Peter N Fish, Doantrang Du

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Farhan KhalidDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.
Anosh Aslam KhanDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.
Hardikkumar BhanderiDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.
Peter N FishDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.
Doantrang DuDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infective Endocarditis is characterized by inflammation of the heart's inner lining and valves which can lead to valve masses made of fibrin, platelets, and the infectious organisms. Patients can present with a wide array of symptoms with neurological symptoms quite rare. Here, we present a case of a 41-year-old who was admitted for IE and later developed an intraparenchymal hemorrhage. A Transesophageal echo (TEE) showed > 2 cm tricuspid valve vegetation and small mitral valve vegetation. After the patient developed confusion an urgent head CT showed a large acute left frontal intra-parenchymal hematoma with intraventricular extension and possible ventricle entrapment. He was treated with emergency decompression hemi-craniotomy and extra ventricular drain placement. A follow-up diagnostic cerebral angiogram revealed a mycotic distal cortical left middle cerebral artery aneurysm for which he underwent Digital Subtraction Angiography (DSA) and embolization of mycotic aneurysm. Neurological complications of IE are rare but life threatening. Early brain imaging is essential for the prompt identification of stroke events, and angiographic evaluation is critical for the diagnosis and management of aneurysms, even when a course of antibiotic therapy is being continued. A timely cardiac surgery to replace vegetative valves is crucial for reducing the adverse events of IE.

Indexed as

Infective EndocarditisIntraparenchymal HemorrhageMycotic AneurysmSeptic EmboliStreptococcus Pneumonia

Identifiers

PMID40487818
PMCPMC12145750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.