Evidence map›Paper›PMID 40487633›Full record

ArticleActa pharmaceutica Sinica. B2025

SMAD4 depletion enhances NHEJ by regulating BRCA1 expression through ARIH1 in pancreatic cancer.

Yiran Song, Yazhi He, Tianyu Yu, Yang Wang, Liwei An, Yang Shi, Yingqun Zhou, Junyi Ju, Feng Wang

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yiran SongDepartment of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, China.
Yazhi HeDepartment of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, China.
Tianyu YuDepartment of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, China.
Yang WangDepartment of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, China.
Liwei AnDepartment of Medical Ultrasound, Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, China.
Yang ShiDepartment of Polymer Therapeutics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen 52074, Germany.
Yingqun ZhouDepartment of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Junyi JuThe Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou 225300, China.
Feng WangDepartment of Gastroenterology, Huadong Hospital, Fudan University, Shanghai 200040, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BRCA1Homologous recombinationNon-homologous end joiningPancreatic cancerSMAD4

Identifiers

PMID40487633
PMCPMC12144992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.