Evidence map›Paper›PMID 40487555›Full record

ArticleCase reports in oncology

Intramedullary Glioblastoma as One of Multiple Radiation-Induced Neoplasms.

Kacper Koczyk, Arkadiusz Nowak, Marcin M Machnicki, Łukasz Zdzisław Michałowski, Edyta Maj, Tomasz Stoklosa, Przemysław Kunert

Abstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Influence of treatment modalities on survival and progression free survival in primary spinal cord glioblastoma: a systematic review and individual participant data meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kacper KoczykDepartment of Neurosurgery, Central Clinical Hospital, Medical University of Warsaw, Warsaw, Poland.
Arkadiusz NowakDepartment of Neurosurgery, Central Clinical Hospital, Medical University of Warsaw, Warsaw, Poland.
Marcin M MachnickiDepartment of Tumor Biology and Genetics, Medical University of Warsaw, Warsaw, Poland.
Łukasz Zdzisław MichałowskiDepartment of Pathology, Medical University of Warsaw, Warsaw, Poland.
Edyta MajSecond Department of Clinical Radiology, Medical University of Warsaw, Warsaw, Poland.
Tomasz StoklosaDepartment of Tumor Biology and Genetics, Medical University of Warsaw, Warsaw, Poland.
Przemysław KunertDepartment of Neurosurgery, Central Clinical Hospital, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Intramedullary glioblastoma is a rare entity comprising 1.4-9% of spinal gliomas. Spinal cord radiation-induced gliomas are unique, with only 13 cases reported to date. Case Presentation: A 53-year-old female with a history of mediastinal Hodgkin lymphoma treated with chemotherapy and radiotherapy who subsequently developed thyroid cancer and breast cancer throughout her life was admitted due to slowly progressing spastic tetraparesis. Cervical MRI revealed an intramedullary lesion at the C4-T1 level, enlarging the spinal cord, with a heterogenous contrast enhancement and a lesion within T1 vertebral body showing contrast enhancement. Whole-body Conclusion: We report a case of an intramedullary glioblastoma in a patient with a history of radiation and multiple neoplasms located at the irradiation field borders. The full molecular analysis allowed for classification of the tumor as glioblastoma, IDH-wildtype (CNS WHO G4), and screening for germinal mutations potentially predisposing to spontaneous neoplasm development.

Indexed as

ATMGlioblastomaIntramedullaryPostradiationSecondary cancerSpinal cord

Identifiers

PMID40487555
PMCPMC12143871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.