Evidence map›Paper›PMID 40487435›Full record

ArticleiScience2025

Early preclinical development of

Deepesh Biswas, Rebecca Kristina Edwin, K Shiva Kumar, Anwar Alam, Dhiraj Kumar, Sandipan Chakraborty, Gopalakrishnan Bulusu, Farhan Jalees Ahmad, Gautham G Shenoy, Lakshyaveer Singh and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Induced alanine auxotrophy as a therapeutic strategy againstbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Deepesh BiswasDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Rebecca Kristina EdwinDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
K Shiva KumarDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Anwar AlamDepartment of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, India.
Dhiraj KumarCellular Immunology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India.
Sandipan ChakrabortyDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Gopalakrishnan BulusuDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Farhan Jalees AhmadDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.
Gautham G ShenoyManipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal 576104, India.
Lakshyaveer SinghTuberculosis Aerosol Challenge Facility, International Centre of Genetic Engineering and Biotechnology, New Delhi 110067, India.
Mansi AgarwalIndian Council of Medical Research-Centre for Cancer Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Fouzia SirajIndian Council of Medical Research-Centre for Cancer Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Srinivas OrugantiDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Parimal MisraDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Nasreen Zafar EhteshamDepartment of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, India.
Manojit PalDr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500046, India.
Seyed Ehtesham HasnainDepartment of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for new anti-tubercular agents is vital for the fight against

Indexed as

Biological sciencesMedical MicrobiologyMicrobiologyNatural sciencesPharmacology

Identifiers

PMID40487435
PMCPMC12144419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.