ReviewFrontiers in pharmacology2025
Research progress in the treatment of non-scarring alopecia: mechanism and treatment.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial: Prevention and treatment of skin diseases.Frontiers in pharmacology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Non-scarring alopecia, encompassing androgenetic alopecia (AGA), alopecia areata (AA), and telogen effluvium (TE), is a common skin condition that significantly impacts both the physical and psychological wellbeing of affected individuals. This review aims to delve into the multifactorial etiology of non-scarring alopecia and to critically assess the current and emerging treatment options available for management. Methods: The review methodology involved a comprehensive literature search in PubMed and Web of Science, focusing on the genetic, environmental, and psychological factors that contribute to the development of non-scarring alopecia. The search included studies published from 2004 to 2024, primarily in English, to incorporate both foundational and recent advancements in the field. The inclusion criteria encompassed clinical trials, meta-analyses, and high-quality observational studies investigating the pathogenesis and treatment of non-scarring alopecia. Case reports, editorials, and studies with insufficient methodological details were excluded. Additionally, this review evaluated FDA-approved treatments (e.g., minoxidil and finasteride) and emerging therapeutic agents, such as Janus kinase (JAK) inhibitors and natural remedies, with an emphasis on their mechanisms, efficacy, and safety profiles. Results: The findings from this review indicate that the currently available treatments, such as topical and oral minoxidil, oral finasteride, and Janus kinase (JAK) inhibitors, exhibit limited efficacy and are associated with adverse effects. In contrast, natural remedies have shown promise as alternative treatments, potentially offering more effective management with fewer side effects. Discussion: The conclusion drawn from this review is that there is a significant potential for natural products and innovative drugs to provide effective treatment options for non-scarring alopecia. However, the assumption that natural remedies universally have fewer side effects than conventional treatments requires careful consideration, as their safety profiles vary. This underscores the need for further research and development in this area to improve patient outcomes and quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.