ArticleToxicology reports2025
The role of global DNA methylation in citrinin induced toxicity:
Article in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Selected Nutraceuticals in Metabolic Syndrome: Molecular Mechanisms and Clinical Implications.Biomedicines · 2026Review
- HPV-Driven Cervical Carcinogenesis: Genetic and Epigenetic Mechanisms and Diagnostic Approaches.International journal of molecular sciences · 2026Review
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Authors and funding
2 authors.
Funding
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Abstract
Citrinin (CIT) is a widely occurring mycotoxin which exhibits a variety of toxic effects. Only a few countries have legal limitations on CIT content in foods, despite the dangers it presents. The aim of this study is to investigate the effects of CIT on DNA methylation in SH-SY5Y and HK-2 cells and to perform docking studies to explore the possible interactions between CIT and DNMT enzymes. In SH-SY5Y cells, global DNA methylation levels increased by 1.90-fold (p < 0.05) and 1.50-fold (p < 0.05) at 50 and 100 μM of CIT, respectively. In HK-2 cells, the increase was 3.17-fold (p < 0.05) following exposure to 50 μM of CIT. In SH-SY5Y cells,
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