ArticleJournal of oral biology and craniofacial research
Acute oral toxicity and mucosal irritation of a mouthwash containing chlorhexidine and chlorine dioxide in animal models.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background: Halitosis is primarily caused by bacterial activity in the oral cavity. Chlorhexidine (CHX) is a widely used antimicrobial mouthwash but has notable side effects. Chlorine dioxide (ClO Material and method: Mice were administered a single oral dose of a mouthwash containing 0.5 % CHX and 2.5 % ClO Result: No mortality or significant clinical toxicity was observed in mice. Only transient ocular irritation occurred in 30 % of the test group. Conclusion: The combination of 0.5 % CHX and 2.5 % ClO
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