Evidence map›Paper›PMID 40487338›Full record

ArticleJournal of orthopaedics2025

Predictive value of the 5-item modified frailty index in adverse outcomes in total elbow arthroplasty: A machine-learning model analysis.

Yasmin Alamdeen Shahzada, Matthew Smith, Pratiik Kaushik, Josh Setliff, Haleigh Hopper, Brigitte Lieu, James Satalich, Jennifer Vanderbeck

Abstract read
In one paragraph

Article in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yasmin Alamdeen ShahzadaDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Matthew SmithDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Pratiik KaushikDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Josh SetliffDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Haleigh HopperDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Brigitte LieuDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
James SatalichDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.
Jennifer VanderbeckDepartment of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The modified frailty index (mFI-5) is a five factor risk stratification tool predicated on functional status and key medical comorbidities. mFI-5 scores have already demonstrated potential for predicting adverse outcomes after common orthopaedic procedures. The aim of this study was to capitalize upon this potential and leverage machine learning analysis to (1) further interrogate the utility of the mFI-5 as a risk stratification tool, and (2) develop an algorithm with predictive value for adverse outcomes after total elbow arthroplasty (TEA). Methods: A retrospective review of patients who underwent TEA from 2010 to 2020 was conducted using the American College of Surgeons National Surgery Quality Improvement Program (NSQIP) database. Postoperative complications were analyzed as summative binary variables representing the rate of complications such as mortality, readmission, reoperation, extended hospital length of stay (LOS), and discharge to a non-home destination. Univariate and multivariate analysis were performed to determine the relationship between mFI-5 and postoperative complications at the p < 0.05 level. An XGBoost binary classifier was trained to predict significant associations identified in the multivariate regression. SHAP model explainability determined the relative importance of each mFI-5 component. Results: A total of 725 patients (mean age 65.7 Conclusion: mFI-5 scores have high predictive value for longer hospital stays and non-home discharge after TEA. There is growing evidence for using frailty indices to stratify risk and the model developed in this study may serve as a prototype for future clinical decision-making tools.

Indexed as

Frailty indexMachine learningTotal elbow arthroplasty

Identifiers

PMID40487338
PMCPMC12141095

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