Evidence map›Paper›PMID 40487177›Full record

ReviewMaterials today. Bio2025

Transforming spinal surgery with innovations in biologics and additive manufacturing.

Xinggui Tian, Yakui Liu, Suihong Liu, Qinyu Tian, Deepak Bushan Raina, Michael Gelinsky, Stefan Zwingenberger

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Xinggui TianUniversity Center of Orthopaedic, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology, Dresden, 01307, Germany.
Yakui LiuCenter for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at TUD Dresden University of Technology, Dresden, 01307, Germany.
Suihong LiuEngineering Science and Mechanics Department, Penn State University, University Park, 16802, PA, USA.
Qinyu TianDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region of China.
Deepak Bushan RainaDepartment of Clinical Sciences Lund, Orthopaedics, Faculty of Medicine, Lund University, Lund, 22185, Sweden.
Michael GelinskyCenter for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at TUD Dresden University of Technology, Dresden, 01307, Germany.
Stefan ZwingenbergerUniversity Center of Orthopaedic, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology, Dresden, 01307, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synergistic integration of biologics and additive manufacturing (AM) technologies has catalyzed groundbreaking advancements in spinal surgery. These innovations address persistent challenges, such as optimizing fusion outcomes, enhancing tissue regeneration, and achieving precise anatomical compatibility. Biologics have transformed spinal fusion by facilitating bone formation and promoting osteointegration through refinements in traditional materials and cutting-edge biologic developments. Concurrently, AM technologies, including 3D printing and biofabrication, enable the design and production of patient-specific implants and bioengineered scaffolds, significantly enhancing surgical precision and improving treatment outcomes. This review underscores the transformative synergy of biologics and AM, offering a comprehensive exploration of their applications in preclinical research and clinical practice. Together, these synergistic advancements are redefining the field of spinal surgery, driving the evolution of personalized and innovative treatment paradigms.

Indexed as

Additive manufacturingBiologicsRegenerative medicineSpine surgery

Identifiers

PMID40487177
PMCPMC12145720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.