Evidence map›Paper›PMID 40487157›Full record

ArticleMaterials today. Bio2025

Fe-curcumin nanozymes-mediated reactive oxygen species scavenging and anti-apoptotic effects on age-related cataracts.

Xiang Gao, Kewei Li, Yan Huang, Ziyan Long, Yongguo Xiang, Wendi Zheng, Hong Cheng, Huijie Cao, Wenjuan Wan, Shijie Zheng and 2 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiang GaoThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Kewei LiThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Yan HuangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Ziyan LongThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Yongguo XiangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Wendi ZhengThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Hong ChengThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Huijie CaoThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Wenjuan WanThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Shijie ZhengThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.
Xianwen WangSchool of Biomedical Engineering, Anhui Medical University, Hefei, 230032, PR China.
Ke HuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of the National Clinical Research Center for Ocular Diseases, Chongqing, 400016, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related cataracts (ARCs) are major causes of vision impairment globally, primarily resulting from oxidative stress-induced senescence and apoptosis in lens epithelial cells (LECs). In this study, a sodium selenite-induced oxidative stress cataract model in neonatal rats was used to mimic ARC pathology. We investigated the therapeutic potential of Fe-curcumin nanozymes in delaying ARC progression by targeting cellular senescence and oxidative injury.

Indexed as

ApoptosisCataractCurcuminNanozymesSenescence

Identifiers

PMID40487157
PMCPMC12141545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.