Evidence map›Paper›PMID 40487154›Full record

ArticleMaterials today. Bio2025

Synchronous bacterial barrier and exudate absorption: A novel dual-function dressing strategy for pin-site infection prevention.

Bing Liang, Sha Zhou, Linyuan Xue, Qizun Wang, Qianqian Li, Zihan Zheng, Xinyue Ma, Jiyixuan Li, Li Sun, Kunyue Xing and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bing LiangCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Sha ZhouCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Linyuan XueCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Qizun WangDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, China.
Qianqian LiDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, China.
Zihan ZhengCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Xinyue MaCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Jiyixuan LiCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Li SunCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Kunyue XingInstitute of Health Informatics, Faculty of Population Health Sciences, University College London, London, NW1 2DA, United Kingdom.
Xiaobo WenCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Xiaolin WuDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, China.
Miao ZhangCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.
Dongming XingCancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong, 266071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Open pin-site wounds, with infection rates of 11 %-100 %, pose significant clinical challenges, affecting millions globally and often leading to life-threatening complications. Current dressings fail to simultaneously block bacterial invasion and manage internal wound infection, necessitating innovative solutions. This study introduces PINSHIELD, a dual-functional dressing that externally seals wounds while efficiently managing exudate to mitigate pin-site infections (PSI). The external shell provides a physical barrier, while the embedded zinc alginate-polyurethane (ZAPU) layer combines active antibacterial properties with passive bacterial adhesion. The optimized ZAPU structure absorbs exudate and regulates the wound microenvironment, inhibiting bacterial proliferation and limiting infection spread.

Indexed as

Exudate absorptionOsteomyelitisPin-site infectionStaphylococcus aureus, transcriptomic and metabolomic analyses

Identifiers

PMID40487154
PMCPMC12144502

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.