ArticleEuropean heart journal. Case reports2025
Serial inflammation imaging with pericoronary adipose tissue in patients with immunoglobulin G4-related coronary periarteritis: a case report.
Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- From clinical observation to shared knowledge: the European Heart Journal Case Reports Cases of the year 2025.European heart journal. Case reports · 2026Article
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3 authors.
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Abstract
Background: Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated inflammatory disease that infrequently involves the coronary arteries. Given that pericoronary adipose tissue (PCAT) attenuation reflects the degree of inflammation in the coronary arteries, monitoring inflammation with PCAT may enable evaluation of disease activity in IgG4-related coronary periarteritis (CP). Case summary: A 58-year-old man with a history of IgG4-RD presented with ST-segment elevation myocardial infarction. Emergent coronary angiography revealed a severe stenotic lesion in the mid-segment of his left circumflex artery (LCX). Intravascular ultrasound (IVUS) imaging demonstrated thickening of the adventitia, and optical coherence tomography (OCT) showed the formation of vasa vasorum in the proximal segment of the LCX. Along with an elevated IgG4 level (1890 mg/dL), he was diagnosed with IgG4-related CP. Coronary computed tomography angiography (CCTA) after percutaneous coronary intervention (PCI) revealed soft tissue proliferation with elevated PCAT attenuation [PCAT Discussion: In this case, serial PCAT analysis demonstrated resolution of inflammatory activity in response to prednisolone therapy. Serial PCAT imaging may have potential for evaluating disease activity and monitoring response to anti-inflammatory therapy in patients with IgG4-RD.
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