Evidence map›Paper›PMID 40487106›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025

Multi-omics analysis provides new insights into the molecular mechanisms underlying colostral immunoglobulin G absorption in the gut of neonatal goat kids.

Chao Yang, Yan Cheng, Tianxi Zhang, Kefyalew Gebeyew, Amanda Fischer-Tlustos, Leluo Guan, Michael Steele, Zhiliang Tan, Zhixiong He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chao YangNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.
Yan ChengNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.
Tianxi ZhangNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.
Kefyalew GebeyewNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.
Amanda Fischer-TlustosDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G2W1, Canada.
Leluo GuanFaculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Michael SteeleDepartment of Animal Biosciences, University of Guelph, Guelph, ON N1G2W1, Canada.
Zhiliang TanNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.
Zhixiong HeNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early colostrum feeding facilitates the passive transfer of immunoglobulin G (IgG), which contributes to the defensive establishment of neonates; however, the molecular mechanisms of IgG absorption in the small intestine of neonatal mammals remain largely unknown. In this study, a total of 16 neonatal goat kids with similar body weight (2.05 ± 0.31 kg) were selected and randomly assigned to 1 of 2 feeding treatments: normal colostrum feeding (NCF,

Indexed as

Clathrin-mediated endocytosisColostrumImmunoglobulin GMacropinocytosisNeonatal goat kid

Identifiers

PMID40487106
PMCPMC12143632

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.