Evidence map›Paper›PMID 40487068›Full record

ArticlePeerJ2025

Proteomic profiling of the human amniotic stem cell-highly abundant secreted proteins.

Dan He, Yuqiang Cheng, Hongkai Lv, Anqi Geng, Jie Zheng, Lin Dang, Pengfei Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dan HeLaboratory of Animal Center, Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Yuqiang ChengLaboratory of Animal Center, Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Hongkai LvLaboratory of Animal Center, Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Anqi GengResearch & Development Institute, Northwestern Polytechnical University, Shenzhen, Guangdong, China.
Jie ZhengDepartment of Encephalopathy, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Lin DangLaboratory of Animal Center, Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Pengfei LiLaboratory of Animal Center, Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amnion-derived stem cells exhibit several significant advantages, including low immunogenicity, anti-inflammatory, anti-fibrotic, and angiogenic properties, which have garnered considerable attention as a potential source for cell therapy. Numerous studies have demonstrated that proteins secreted by amniotic stem cells play a crucial role in facilitating regenerative processes and reflect the therapeutic benefits across various diseases. Secreted protein products from stem cells offer solutions to challenges in cell therapy, such as improving efficacy during

Indexed as

AmnionMesenchymal Stem CellsProteomeProteomicsAnnexin A2Cells, CulturedCytokinesEpithelial CellsFemaleHumansMacrophagesAnnexin A2CytokinesProteomeANXA2HAECsHAMSCsHuman amniotic stem cellProteomicsSecreted proteins

Identifiers

PMID40487068
PMCPMC12143284

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.