Evidence map›Paper›PMID 40486939›Full record

ArticleInternational journal of cardiology. Heart & vasculature2025

Initial surgery versus conservative management of chronic severe aortic regurgitation in mild symptomatic older patients.

Mijin Kim, Ha Hye Jo, Sahmin Lee, Byung Joo Sun, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Jong-Min Song, Dae-Hee Kim

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mijin KimDivision of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Ha Hye JoDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sahmin LeeDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Byung Joo SunDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ho Jin KimDepartment of Cardiothoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Joon Bum KimDepartment of Cardiothoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sung-Ho JungDepartment of Cardiothoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jong-Min SongDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Dae-Hee KimDivision of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aortic valve replacement (AVR) for severe aortic regurgitation (AR) should be weighed against its operative risk. Mortality is lower in patients with mild symptoms than in those with severe symptoms, while the surgical risk remains high in older patients. This study aimed to evaluate the survival benefit of AVR in mildly symptomatic older patients with severe AR. Methods: From 1996 to 2016, we evaluated 127 older patients with severe AR and mild symptoms. We compared all-cause and cardiac mortality between patients who underwent AVR (OP group, n = 35) and those who were conservatively managed (CONV group, n = 92). Results: Although patients in the OP group were younger than those in the CONV group (74.2 ± 3.2 vs. 77.3 ± 5.2, p = 0.003), no differences were observed in the Society of Thoracic Surgeons score (1.93 ± 0.95 vs. 2.51 ± 1.8, p = 0.12), comorbidity, indexed left ventricular dimensions (LVEDDi: 41.3 ± 4.4 vs. 41.6 ± 5.9 mm/m Conclusion: In mildly symptomatic older patients with severe AR, AVR significantly reduced all-cause and cardiac mortality and should not be withheld solely due to age.

Indexed as

Aortic regurgitationEchocardiographyValve disease surgery

Identifiers

PMID40486939
PMCPMC12141872

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.