Evidence map›Paper›PMID 40486899›Full record

ArticleExperimental and therapeutic medicine2025

Efficacy of intravenous plus intrathecal/intracerebral ventricle injection of tigecycline for post‑neurosurgical intracranial infections due to MDR/XDR

Xia Tian, Xianbing Meng, Lichao Guo, Yan Li, Guoqing Gu, Tianyan Zhang, Rufeng An

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xia TianDepartment of Pharmacy, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.
Xianbing MengDepartment of Neurosurgery, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.
Lichao GuoDepartment of Child Rehabilitation, Taishan District People's Hospital, Taian, Shandong 271000, P.R. China.
Yan LiDepartment of Pharmacy, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.
Guoqing GuDepartment of Pharmacy, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.
Tianyan ZhangDepartment of Pharmacy, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.
Rufeng AnDepartment of Pharmacy, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong 271000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial infection is a complication of neurosurgery that can lead to severe neurological complications, greatly increasing the risk of mortality. Intracranial infection caused by multidrug-resistant

Indexed as

acinetobacter baumanniiextensive drug resistantintracerebralmultidrug-resistanttigecycline

Identifiers

PMID40486899
PMCPMC12141990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.