ArticleJSES international2025
Long-term nonsteroidal anti-inflammatory drug use is associated with rotator cuff tears in adult patients.
Article in JSES international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: To determine if long-term nonsteroidal anti-inflammatory drug (NSAID) is associated with rotator cuff tears (RCTs) in an adult population. Methods: A retrospective study using a national database was performed. All patients with a diagnosis of long-term NSAID use with active records for at least 1 year or 2 years were identified. These patients were matched 1:1 to controls without NSAID use based on age, gender, and Charlson comorbidity index. Rates of new rotator cuff tendon tears were compared. Subgroup analyses in the following age ranges for each sex were done: 35-45, 46-55, 56-65, and 66-75. Results: Out of 499,240 patients with chronic NSAID use, 10,180 patients sustained a RCT compared to 7471 of the control patients (2.04% vs. 1.50%, respectively; odds ratio [OR]: 1.18; 95% confidence interval [CI]: 1.14-1.21; Conclusion: Long-term NSAID use is associated with an increased incidence of rotator cuff tendon tears at the 1- and 2-year follow-up periods in adult patients, particularly those in the 46-55 age range.
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