Indoor endotoxin and house dust mite concentrations in the canine homologue of human atopic dermatitis.

Yunji Song, Yeji Kim, Jihyun Kim, Ha-Jung Kim

Abstract read

In one paragraph

Article in One health (Amsterdam, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

4 authors.

Yunji SongDepartment of Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, South Korea.

Yeji KimDepartment of Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, South Korea.

Jihyun KimDepartment of Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, South Korea.

Ha-Jung KimDepartment of Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Household endotoxin exposure and house dust mite (HDM) allergens have been recently gaining attention for their immunological potential to affect allergic symptoms. Although dogs are spontaneous models of human atopic dermatitis (AD), there are few studies exploring their relationship. The aim of this study is to analyze the effects of HDM and endotoxin concentrations on AD in dogs and compare their immunological profiles with humans. Methods: We graded the canine AD Extent and Severity Index-4 (CADESI-4), Pruritus Visual Analogue Scale (PVAS), and transepidermal water loss (TEWL) in dogs with ( Results: Both the Conclusions: Indoor HDM exposure is associated with decreased TEWL, and endotoxin concentrations may contribute to the mitigation of CAD symptoms.

Indexed as

Atopic dermatitisCompanion dogsEndotoxinEnvironmental factorsHouse dust miteHygiene hypothesisIndoor factor

Identifiers

PMID40486749

DOI10.1016/j.onehlt.2025.101076

PMCPMC12143665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.