Evidence map›Paper›PMID 40486623›Full record

ArticleAnnals of medicine and surgery (2012)2025

Clinical characteristics and predictors of survival in 284 patients with recurrent epithelial ovarian cancer: a large-scale retrospective analysis.

Shahrzad Sheikhhasani, Azam Sadat Moosavi, Setareh Akhavan, Narges Zamani, Elahe Rezayof, Mina Sadat Mosavat

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Shahrzad SheikhhasaniDepartment of Gynecology Oncology, Tehran University of Medical Sciences, Valie-E-Asr Hospital, Tehran, Iran.
Azam Sadat MoosaviDepartment of Gynecology Oncology, Tehran University of Medical Sciences, Valie-E-Asr Hospital, Tehran, Iran.ORCID https://orcid.org/0000-0003-3152-6999
Setareh AkhavanDepartment of Gynecology Oncology, Tehran University of Medical Sciences, Valie-E-Asr Hospital, Tehran, Iran.ORCID https://orcid.org/0000-0001-9338-3861
Narges ZamaniDepartment of Gynecology Oncology, Tehran University of Medical Sciences, Valie-E-Asr Hospital, Tehran, Iran.ORCID https://orcid.org/0000-0002-9128-7224
Elahe RezayofVali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0177-1846
Mina Sadat MosavatDepartment of Gynecology Oncology, Tehran University of Medical Sciences, Valie-E-Asr Hospital, Tehran, Iran.ORCID https://orcid.org/0009-0006-1379-7436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to analyze clinical characteristics, recurrence patterns, and survival predictors in patients with recurrent epithelial ovarian cancer. Methods: We conducted a retrospective analysis of 284 patients with recurrent epithelial ovarian cancer treated at our institution between 2012 and 2022. Clinical data, recurrence patterns, treatment modalities, and survival outcomes were evaluated. Kaplan-Meier analysis and Cox proportional hazards models were used to assess survival and identify prognostic factors. Results: The mean age at recurrence was 54.47 years. Multiple site recurrence (50.70%) was the most common, followed by peritoneal (21.47%) and distant metastases (15.84%). Median progression-free survival (PFS) and overall survival (OS) were 5.00 and 23.00 months, respectively. Retroperitoneal recurrence was associated with better survival compared to distant recurrence (median OS 29.00 vs 16.00 months, Conclusion: Recurrence patterns and timing significantly impact survival in recurrent ovarian cancer. Complete cytoreduction, tumor grade, and initial stage are crucial prognostic factors. These findings emphasize the need for personalized treatment strategies and continued research into novel therapeutic approaches.

Indexed as

cytoreductive surgeryovarian cancerprognostic factorsrecurrencesurvival

Identifiers

PMID40486623
PMCPMC12140724

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.