ArticleAnnals of medicine and surgery (2012)2025
Evaluating the influence of vitamin K supplementation on bone markers in hemodialysis patients.
Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- LP533401 treatment alters vitamin K metabolism, bone Gla-OC/Glu-OC ratios, and improves mineral status of the skeleton in rats with chronic kidney disease.Frontiers in pharmacology · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to assess the impact of vitamin K supplementation on bone factors in hemodialysis patients. Methods: In this randomized clinical trial, 80 patients with end-stage renal disease undergoing hemodialysis, aged over 18 years, and who had been on chronic dialysis for at least 1 month without taking warfarin, underwent blood tests for bone factors. Subsequently, patients were randomly assigned to either the treatment or control group using block randomization. The effects of vitamin K on bone activity markers were evaluated in both groups. Data collected were analyzed using SPSS-24 after encoding and entry. Results: The study comprised 41 patients in the treatment group and 39 in the control group. The average age was 53.17 ± 9.88 years in the treatment group and 54.61 ± 10.71 years in the control group. There was a significant difference in the mean albumin levels post-supplementation between the treatment (4.62 ± 0.47) and control groups (4.78 ± 0.51) ( Conclusions: The findings of this study indicate that supplementation with vitamin K, along with vitamin D and calcium, could lead to the fortification of bone tissue and mineralization, subsequently reducing the occurrence of fractures in dialysis patients.
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