Evidence map›Paper›PMID 40486479›Full record

ArticleCureus2025

Comparison of Polyglactin 910 With Barbed Sutures for Vaginal Cuff Closure Time in Patients Undergoing Total Laparoscopic Hysterectomy.

Mahendra G, Preethi Maski, Subbappa K, Ramesh Babu

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahendra GDepartment of Obstetrics and Gynecology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, IND.
Preethi MaskiDepartment of Obstetrics and Gynecology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, IND.
Subbappa KDepartment of Obstetrics and Gynecology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, IND.
Ramesh BabuDepartment of Obstetrics and Gynecology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Total hysterectomy is among the most performed gynecological surgeries globally, with a significant shift toward laparoscopic approaches for benign uterine conditions. While laparoscopic hysterectomy offers several benefits, such as reduced pain, shorter recovery, and fewer complications, challenges in laparoscopic suturing of the vaginal cuff remains. The introduction of barbed sutures, which eliminate the need for knotting, has been proposed as an effective alternative to traditional suturing. Methods A prospective, two-arm, randomized, single-center study was conducted at Adichunchanagiri Institute of Medical Sciences, Karnataka, India, from May to October 2024. Sixty adult women, aged 30-75 years, scheduled for total laparoscopic hysterectomy (TLH) due to benign uterine pathologies were enrolled. Participants were randomly assigned to one of two groups using a pre-sealed envelope: the unidirectional barbed suture group with a triangular end stopper and a black needle or the polyglactin 910 suture group with a black needle. Primary and secondary outcomes included comparison of vault closure time, total operative time, postoperative pain (measured by the visual analog scale), intraoperative handling of sutures, and vaginal cuff-related complications. Results The barbed suture group had a significantly shorter mean vault closure time (6.94 ± 3.39 minutes vs 11.75 ± 4.59 minutes; p = 0.00002) and total operative time (102.27 ± 22.27 minutes vs 131.10 ± 24.99 minutes; p = 0.000015) as compared to the polyglactin 910 suture group. Postoperative pain levels and intraoperative handling properties of the sutures were comparable between the two groups. No vaginal cuff-related complications were observed in either group. Conclusion The barbed suture significantly reduced vault closure time and total operative time compared to the polyglactin 910 suture, suggesting that it may enhance the efficiency of laparoscopic vaginal cuff closure. However, both suture types demonstrated comparable postoperative pain and complication rates. These findings support the use of both sutures as safe and effective options for TLH, with the barbed suture offering advantages in vault closure time and overall surgical time.

Indexed as

barbed suturepolyglactin 910 suturepost-operative paintotal laparoscopic hysterectomyvaginal cuff complicationsvault closure time

Identifiers

PMID40486479
PMCPMC12144665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.