Evidence map›Paper›PMID 40486449›Full record

ArticleCureus2025

Balloon-Occluded Retrograde Transvenous Obliteration (BRTO) for Gastric Varices: A Single-Center Experience in the Middle East.

Muneera Almohannadi, Ahmed Omar, Ali Barah, Anwar I Joudeh, Ahmed M Badi, Yousra Ali, Yousef Yahia, Rajvir Singh, Betsy Varughese, Rafie Yakoob

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muneera AlmohannadiGastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.
Ahmed OmarRadiology, Hamad Medical Corporation, Doha, QAT.
Ali BarahRadiology, Hamad Medical Corporation, Doha, QAT.
Anwar I JoudehInternal Medicine, Hamad Medical Corporation, Doha, QAT.
Ahmed M BadiInternal Medicine, Hamad Medical Corporation, Doha, QAT.
Yousra AliGastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.
Yousef YahiaGastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.
Rajvir SinghAcute Care Surgery, Hamad Medical Corporation, Doha, QAT.
Betsy VarugheseGastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.
Rafie YakoobGastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aims to assess the short- and long-term outcomes of balloon-occluded retrograde transvenous obliteration (BRTO) in managing gastric varices (GV).

methodsWe conducted a retrospective chart review of all patients who underwent BRTO for actively bleeding or at high-hemorrhagic-risk GV secondary to liver cirrhosis at our facility from January 2007 to December 2019. Descriptive and analytical statistics were used to evaluate short- and long-term postprocedural outcomes. Univariate and multivariate analyses were used to identify significant factors associated with mortality. Survival was assessed using the Kaplan-Meier method. A p-value of <0.05 was considered statistically significant.

resultsA total of 35 patients (mean age: 53.3 ± 9.9 years) were included, with the majority being men (N = 29, 82.9%). Most patients had Child-Pugh classification A (N = 14, 40%) or B (N = 13, 37.1%). Twenty-two patients (62.9%) underwent BRTO emergently, and 13 (37.1%) underwent the procedure prophylactically. Collateral embolization and hemostasis were achieved in all but one patient. Gastric variceal recurrence occurred in five patients (14%), and esophageal varices (EV) worsened in three (9%). During a mean follow-up of 96.2 ± 9 months, seven patients (20%) experienced variceal bleeding episodes, all managed endoscopically. The estimated post-BRTO survival rates at 1, 3, 5, and 10 years were 82.1%, 82.1%, 76.6%, and 68.1%, respectively. Preprocedural Child-Pugh classification A or B and total bilirubin levels < 3.5 mg/dL were associated with better survival rates.

conclusionBRTO is a safe and effective treatment for both emergent bleeding control and prophylactic management of high-hemorrhagic-risk GV.

Indexed as

brtoembolizationgastric varicesliver cirrhosisportal hypertensionportosystemic shuntvariceal bleeding

Identifiers

PMID40486449
PMCPMC12145494

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