Evidence map›Paper›PMID 40486439›Full record

ReviewCureus2025

A Review of Early Childhood Caries: Risk Factors, Management, and Policy Recommendations.

Niyomi S Patel, Miral Mehta, Yihan Fu, Vishnu Desai, Hetvi S Lala, Het Parikh, Mansi M Patel, Urja B Thakor

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prefabricated zirconia crowns versus alternative full-coverage restorations for primary anterior teeth: a systematic review of clinical outcomes.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
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  5. Streptococcus dentisani and Streptococcus mutans in dental biofilm of preschoolers with and without early childhood caries: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Niyomi S PatelDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Miral MehtaDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Yihan FuDepartment of General Dentistry, SmileBuilderz, Lancaster, USA.
Vishnu DesaiDepartment of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Hetvi S LalaDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Het ParikhDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Mansi M PatelDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.
Urja B ThakorDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initially, the American Academy of Pedodontics and the American Academy of Pediatrics (AAP) jointly addressed severe tooth decay related to bottle use by issuing a statement on Nursing Bottle Caries. However, over the next two decades, the American Academy of Pediatric Dentistry (AAPD) expanded its understanding, recognising that early childhood caries (ECC) resulted from various inadequate feeding practices, leading to the adoption of the broader term "ECC" to better reflect its complex causes. This review discusses ECC: its prevalence, risk factors, effects, prevention, early detection, and treatment. It emphasises diet, oral hygiene, socio-economic status, and the importance of parental education and access to dental services in ECC. The aim is to synthesise research to improve ECC understanding and management. This paper reviews the causes and effects of ECC on oral health. Data were obtained from databases like PubMed and Google Scholar, using relevant keywords. The review used English-language articles, including research and policies. This review reveals that ECC is a complex disease causing severe tooth decay in young children. ECC development is influenced by diet, oral hygiene, quality of life, fluoride intake, oral microbiota, environmental factors, and feeding practices. It can lead to short- and long-term issues, like pain, infection, eating and speech difficulties, poor development, and enamel defects. Effective prevention requires multifaceted strategies involving home care, dental interventions, community support, and policies. A major, yet preventable, disease, ECC significantly impacts global oral health, particularly in deprived children. Starting with the first tooth, it harms development and well-being. Prevention relies on public education, interprofessional collaboration, and implementing AAPD policy recommendations.

Indexed as

early childhood cariesfluoridemanagementpediatric oral healthpediatric preventive dentistry

Identifiers

PMID40486439
PMCPMC12145511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.