Evidence map›Paper›PMID 40486354›Full record

ArticleCureus2025

Signet Ring Cell Carcinoma of the Colon With Spermatic Cord Metastasis.

Rin Morishita, Rina Fujiwara-Tani, Ruiko Ogata, Naokuni Tatsumoto, Hiroki Kuniyasu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rin MorishitaMolecular Pathology, Nara Medical University, Kashihara, JPN.
Rina Fujiwara-TaniMolecular Pathology, Nara Medical University, Kashihara, JPN.
Ruiko OgataMolecular Pathology, Nara Medical University, Kashihara, JPN.
Naokuni TatsumotoSurgery, Miyoshi Central Hospital, Miyoshi, JPN.
Hiroki KuniyasuMolecular Pathology, Nara Medical University, Kashihara, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of metastatic signet ring cell carcinoma (SRC) of the colon involving the right spermatic cord and testis following a right hemicolectomy. A 53-year-old male presented to our hospital in August 2020 with abdominal distension. Colonoscopy revealed a stenotic tumor in the transverse colon, and curative right hemicolectomy was performed. Histopathological examination confirmed colorectal cancer (CRC), classified as Stage IIIc. Postoperatively, capecitabine was administered for six months. In October 2021, the patient revisited our hospital with right scrotal swelling and pain. Although tumor markers were negative, CT revealed a tumor in the spermatic cord. Subsequently, orchiectomy and spermatic cord excision were performed. Histopathological findings confirmed SRC, consistent with the primary colon cancer diagnosed at age 53, and the lesion was considered a metastasis. This case represents an extremely rare occurrence of CRC of the colon, further complicated by metastasis to the spermatic cord, an uncommon metastatic site for CRC.

Indexed as

colonic signet ring cell carcinomametastasisperitoneal disseminationseminal cord metastasissignet ring cell carcinoma

Identifiers

PMID40486354
PMCPMC12145856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.