Evidence map›Paper›PMID 40486345›Full record

ArticleCureus2025

Case Series on Varied Presentations of Amlodipine Toxicity.

S Sridhar, Sandhiya Narendiran, Murugan K R, A Marimuthu, Sahasyaa Adalarasan, Yogesh S, S Shivamalarvizhi, Hariharan C

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S SridharInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.
Sandhiya NarendiranInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.
Murugan K RInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.
A MarimuthuInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.
Sahasyaa AdalarasanInternal Medicine, Madras Medical College, Chennai, IND.
Yogesh SInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.
S ShivamalarvizhiInternal Medicine, Madras Medical College, Chennai, IND.
Hariharan CInternal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium channel blockers (CCBs) are among the most widely prescribed drugs for cardiovascular illnesses. Angina pectoris, cardiac arrhythmias, hypertension, and other conditions are treated with calcium channel blockers (CCBs). Both immediate-release and extended-release versions of these drugs are available; the latter are often used in therapeutic settings. While extended-release CCB overdoses can cause delayed start of dysrhythmias, shock, sudden cardiac collapse, and intestinal ischemia, immediate-release CCB overdoses are characterized by rapid progression to hypotension, bradydysrhythmia, and cardiac arrest. The present case series consists of five cases of amlodipine toxicity that were treated at Rajiv Gandhi General Government Hospital and had a range of clinical manifestations. The present case series also includes two cases of non-cardiogenic pulmonary edema, a rare presentation of amlodipine poisoning.

Indexed as

amlodipine-amlodipine toxicitycalcium channel blockersessential hypertensionhypertension

Identifiers

PMID40486345
PMCPMC12144486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.