Evidence map›Paper›PMID 40486310›Full record

ArticleCureus2025

Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome Triggered by Missed Dialysis: A Case Report.

Kesava Manikanta Achuta, Venkata Vedantam, Sai Karthik Kommineni, Neethu Vedantam, Kyasa S Venisha

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kesava Manikanta AchutaInternal Medicine, Garden City Hospital, Michigan State University, Dearborn Heights, USA.
Venkata VedantamInternal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Sai Karthik KommineniInternal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Neethu VedantamInfectious Diseases, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Kyasa S VenishaRadiology, Aditya Diagnostics, Godavarikhani, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bradycardia, renal failure, atrioventricular (AV) nodal blocker usage, shock, and hyperkalemia are the hallmarks of BRASH syndrome, a complex medical emergency. Despite having a high mortality rate, BRASH syndrome is underdiagnosed and frequently develops from the combined effects of renal failure and drug toxicity. Here, we present the case of an 86-year-old woman with end-stage renal disease (ESRD) who developed BRASH syndrome due to missed dialysis sessions, exacerbated by low-dose beta-blocker therapy. This case emphasizes how crucial it is to identify BRASH syndrome early, treat it quickly, and address its untoward events to avoid fatalities.

Indexed as

bradycardiabrash syndromeend-stage renal diseasehyperkalemiarenal dysfunction

Identifiers

PMID40486310
PMCPMC12144664

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.