ReviewCureus2025
Restoration of Sagittal Alignment and Pulmonary Function With Percutaneous Vertebral Body Augmentation for Painful Osteoporotic Vertebral Compression Fractures: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Advantages of TiRobot-assisted surgery in the treatment of osteoporotic thoracolumbar compression fractures: a meta-analysis based on multiple clinical indicators.Journal of robotic surgery · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sagittal spinal malalignment is associated with functional disability. Therefore, a key question in treating patients with painful osteoporotic vertebral compression fractures (OVCFs) is whether vertebral augmentation improves sagittal alignment and its associated outcomes. In a systematic literature review based on interventional and observational studies, we evaluated the effect of percutaneous vertebral body augmentation on sagittal alignment and pulmonary function in patients with painful OVCFs. In November 2022 and December 2023, we searched for relevant studies in Medline, Embase, SCOPUS, Web of Science, the Cochrane Central Registry of Controlled Trials, and five trial registries. In total, 15 cohort studies and two non-randomized clinical trials met our inclusion criteria. Participants in these studies had painful OVCFs treated with vertebral body augmentation. Sagittal alignment outcomes from nine articles represented 456 participants with mean ages from 69.3 to 80.8 years, and pulmonary function outcomes from eight articles represented 343 participants with mean ages from 69.1 to 75.7 years. The quality assessment tool for quantitative studies by the Effective Public Health Practice Project assessed the risk of bias (RoB). Mean pre- and postoperative outcome values were calculated for all included studies and those without a high RoB. None of the sagittal alignment parameters improved after vertebral augmentation, and no additional deformity was detected. Vertebral augmentation positively affected pulmonary function, as measured by the percentage of predicted values, and reduced perceived pain levels and functional disability. Data in the included studies were incomplete due to variability in chosen outcomes and follow-up time points. The incomplete data curtailed our data analysis and only allowed cautious conclusions. Variations in study populations and protocols highlight the need for standardized reporting and follow-up in future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.