ArticleGastro hep advances2025
The Involvement of Oral Pathogenic Bacteria,
Article in Gastro hep advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies.MedComm · 2026Review
- IntratumoralAnnals of gastroenterological surgery · 2026Article
- Deciphering intratumoral microbiota in digestive system tumors: mechanisms and emerging therapeutic strategies.Frontiers in cellular and infection microbiology · 2026Review
- The intratumoral microbiome in colorectal cancer: origins, microenvironmental interactions, and new horizons in precision medicine.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: While esophageal microbiota is known to be altered in patients with esophageal adenocarcinoma (EAC), specific bacterial species contributing to the pathogenesis remain unclear. We aimed to identify bacteria associated with the pathogenesis of EAC and to investigate their potential role. Methods: Microbiota in EAC tissues was explored by 16S-rRNA sequencing. The impact of intratumoral bacteria on tumor microenvironment was histologically evaluated. The influence by pathological bacteria on cancer cells was examined by the treatment of OE33 cell line with cultural supernatant of bacteria. Results: Oral pathogenic bacteria previously reported to increase in colorectal cancer patients were detected in 7 out of 31 EAC patients and were associated with poor prognosis. Intratumoral bacterial infiltration was significantly accompanied with local neutrophil infiltration and nuclear positivity of NF-κB in cancer cells. Furthermore, the culture supernatant of Conclusion: Intratumoral microbiota, especially the infiltration of oral pathogenic bacteria such as
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.