ArticleJournal of arthropod-borne diseases2024
Anti-Malarial Activity of Nano Tannic Acid MgO Extract Alone and Combined with Chloroquine against
Article in Journal of arthropod-borne diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The global rise in malaria parasite resistance to antimalarial drugs necessitates new therapeutic strategies. Medicinal plant extracts, long used in traditional malaria treatment, have shown antiplasmodial potential in recent studies. This study investigated the effects of nano tannic acid MgO (NTA MgO) and chloroquine (CQ), both individually and in combination, on a chloroquine-sensitive Methods: BALB/c mice infected with Results: The ED Conclusion: NTA MgO showed strong antiplasmodial activity both alone and with chloroquine (CQ). The 30% CQ and 70% NTA MgO combination exhibited a significant synergistic effect, highlighting its potential as a new treatment for chloroquine-sensitive malaria and the promise of plant-based nanoparticles against drug-resistant malaria.
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