Evidence map›Paper›PMID 40486118›Full record

ArticleJHLT open2025

The approach to placement of a continuous-flow intracorporeal ventricular assist device in small left ventricle.

Ryaan El-Andari, Josiane Dion, Jennifer Conway, Tara Pidborochynski, Lindsey Carter, Gurmeet Singh, Roderick MacArthur, Steven Meyer, Devilliers Jonker, Darren H Freed and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ryaan El-AndariDivision of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Josiane DionDepartment of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Jennifer ConwayDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Tara PidborochynskiDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Lindsey CarterDepartment of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Gurmeet SinghDivision of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Roderick MacArthurDivision of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Steven MeyerDivision of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Devilliers JonkerDivision of Congenital Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Darren H FreedDivision of Congenital Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Holger BuchholzDivision of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The HeartMate 3 (HM3) has become among the most widely utilized durable left ventricular (LV) assist devices (LVAD) owing to reduced rates of pump thrombosis, bleeding, and stroke. One limitation of the HM3 is its large size, which poses a challenge for implantation in smaller LVs. Herein, we describe a novel technique for durable LVAD implantation in patients with a small LV. Methods: Patients who underwent durable LVAD implantation from January 2020 to August 2024 were included in this study. The modified technique involved excision of the mitral valve (MV) and associated apparatus to create room for the LVAD inflow. The primary outcome was mortality, and secondary outcomes included rates of postoperative complications and hemodynamic parameters. Patient follow-up was until September 2024. Results: Eleven patients were included in this study. All patients received an HM3. The median preoperative LV end-diastolic diameter was 5.1 cm. The median total time on LVAD was 149 days, and overall mortality was 27.2% occurring a median of 204 days post-LVAD implantation. Four patients (36.4%) underwent heart transplantation and 4 (36.4%) were alive on LVAD at last follow-up. Proportions of morbidity included readmission for heart failure ( Conclusions: The small LV has been a significant challenge for durable LVAD insertion and is often considered a contraindication. A modified approach to LVAD insertion, including excision of the MV and associated apparatus and alignment of the LVAD inflow cannula with the MV orifice, allows for LVAD implantation in patients with a small LV.

Indexed as

heart failureleft ventriclemechanical circulatory supportmitral valveventricular assist device

Identifiers

PMID40486118
PMCPMC12142627

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.