ArticleBlood cell therapy2025
PYODERMA GANGRENOSUM WITH NON-PSEUDOMONAL ECTHYMA GANGRENOSUM IN MYELODYSPLASTIC SYNDROME TREATED WITH ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION.
Article in Blood cell therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Co-occurrence of pyoderma gangrenosum (PG) and ecthyma gangrenosum (EG) pose diagnostic and therapeutic challenges in immunocompromised patients. Case Report: A 47-year-old Filipino woman with transfusion-dependent intermediate-risk myelodysplastic syndrome (MDS) was admitted to our institution for allogeneic hematopoietic stem cell transplantation (HSCT). During the preparation for allogeneic HSCT, she developed several erythematous ulcerated lesions on the lower extremities, which were initially managed as PG. Subsequent febrile episodes and worsening lesions with isolated Conclusion: This case highlights the importance of accurate diagnosis and integrated management of complex conditions like PG and EG in immunocompromised patients. The successful resolution of lesions post-HSCT underscores the potential curative role of stem cell transplantation in managing MDS-associated PG.
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