ArticleMedical journal of the Islamic Republic of Iran2025
Evaluation and Comparison of Treatment Response and In-Hospital Prognosis of COVID-19-Related Guillain-Barre Syndrome with Non-COVID-19 Patients.
Article in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The coronavirus disease 2019 (COVID-19) outbreak has caused significant health and social impacts worldwide. Severe acute respiratory syndrome coronavirus 2, the virus responsible for COVID-19, can lead to neurological symptoms, including Guillain-Barré syndrome (GBS). This study aimed to compare the clinical manifestations, electrophysiological characteristics, degree of disability, and treatment outcomes of GBS patients with COVID-19 (COVID-19-related GBS) with GBS patients without COVID-19. Methods: This retrospective cross-sectional multicenter study investigated the clinical characteristics and outcomes of GBS patients with a history of COVID-19. A total of 60 patients with GBS and a history of COVID-19 were included in the COVID-19 group, while 56 patients with GBS without COVID-19 were included in the control group. Demographic, clinical, therapeutic, and prognostic data were compared between the 2 groups. Results: The COVID-19 patients were older (56.2 ± 16.8 vs 47.46 ± 19.25; Conclusion: GBS in COVID-19 patients may have different manifestations and electrophysiological patterns, but the response to treatment and in-hospital prognosis were not different compared with GBS in non-COVID-19 patients.
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