Evidence map›Paper›PMID 40485994›Full record

ArticleJHLT open2025

Responsiveness validity for measures of adjustment to life with a left ventricular assist device: Findings from the MCS A-QOL study.

Elizabeth A Hahn, Larry A Allen, David Cella, David G Beiser, Quin E Denfeld, James Kirklin, JoAnn Lindenfeld, Colleen K McIlvennan, Bernice Ruo, Jeffrey Teuteberg and 9 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03044535 (Mechanical Circulatory Support), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03044535 completednot on this map

Mechanical Circulatory Support: Measures of Adjustment and Quality of Life

TypeobservationalSponsorNorthwestern UniversityRan2016 to 2020Enrolled895ConditionsQuality of Life, Heart Failure, Cardiovascular Diseases
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Elizabeth A HahnMedical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.
Larry A AllenMedicine, University of Colorado, Aurora, CO.
David CellaMedical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.
David G BeiserEmergency Medicine, University of Chicago, Chicago, IL.
Quin E DenfeldNursing, Oregon Health and Science University, Portland, OR.
James KirklinKirklin Solutions Inc., Hoover, AL.
JoAnn LindenfeldMedicine, Vanderbilt University, Nashville, TN.
Colleen K McIlvennanMedicine, University of Colorado, Aurora, CO.
Bernice RuoMedicine, University of California-San Diego, La Jolla, CA.
Jeffrey TeutebergMedicine, Stanford University, Stanford, CA.
Michael KiernanCardiology, Tufts University School of Medicine, Boston, MA.
Liviu KleinMedicine, University of California, San Francisco, CA.
Christopher S LeeNursing, Boston College, Chestnut Hill, MA.
Catherine MurksEmergency Medicine, University of Chicago, Chicago, IL.
Jonathan RichMedicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Josef StehlikMedicine, University of Utah, Salt Lake City, UT.
Mary Norine WalshHeart Failure and Cardiovascular Research Institute, Ascension St Vincent Heart Center, Indianapolis, IN.
Katy BedjetiMedical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.
Kathleen L GradySurgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report evaluated responsiveness validity (sensitivity to change) for five ventricular assist device (VAD)-specific patient-reported outcomes (PROs). Patients at 12 U.S. sites completed PRO measures at months 3 and 6 post-VAD including: Being Bothered by VAD, Self-care and Limitations, Self-efficacy Regarding VAD Self-care, Treatment Satisfaction, VAD Team Communication, Stigma, Kansas City Cardiomyopathy Questionnaire (KCCQ-12), EQ-5D-3L, and Intermacs Post-Implant Quality of Life Form. Statistical methods included linear mixed effect models, analysis of variance methods and Pearson correlation coefficients (r). To evaluate sensitivity to change, VAD change scores were mapped to change in indicator variables (better, no change, worse). The VAD-specific PRO measures demonstrated preliminary evidence of responsiveness to change from month 3 to month 6. Use of these measures may assist VAD clinicians to inform patients about VADs as a treatment option and identify areas of concern that may guide interventions to support adjustment to having a VAD and enhance life quality. Clinical Trial Registration: ClinicalTrials.gov ID: NCT03044535.

Indexed as

Mechanical Circulatory supportPatient-reported outcomesResponsiveness validityVentricular assist device

Identifiers

PMID40485994
PMCPMC12141541

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.