Evidence map›Paper›PMID 40485965›Full record

ArticleJournal of clinical and experimental dentistry2025

Enhancing Shear Bond Strength of Composite to In-Office Bleached Enamel with Biomimetic Remineralizing Agents: An

Sanjana Agarwal, Shashi Rashmi Acharya, Shubha Chhaparwal, Arun Mayya, Akshatha Chatra

Abstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sanjana AgarwalMDS. Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.
Shashi Rashmi AcharyaMDS. Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.
Shubha ChhaparwalMDS. Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.
Arun MayyaMDS. Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal-576104, Karnataka, India.
Akshatha ChatraMDS. Department of Conservative Dentistry and Endodontics, Yenepoya Dental College, Yenepoya (Deemed to be University), 575018, Deralakatte, Mangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bleaching procedures alter enamel microstructure, impacting composite bonding. Biomimetic remineralizing agents may restore the bond strength post-bleaching. This in-vitro study aimed to evaluate and compare the role of remineralizing agents on the shear bond strength of composite to in-office bleached enamel using the total-etch technique. Material and Methods: 28 human maxillary premolars were extracted for orthodontic purposes and split into buccal and palatal halves. The 55 samples were divided into five groups. Bleaching procedure was conducted and remineralizing agents were applied twice daily for 5 minutes over 24 days. The five groups included a negative control (Group 1) and groups treated with GC Tooth Mousse Plus (Group 2), Curodont Repair (Group 3), Regenerate Paste (Group 4), and CTx4 Gel (Group 5). A universal composite restorative was applied after total-etch and adhesive application. Shear bond strength was evaluated using an Instron 3366 universal testing machine with a 0.5mm/min loading rate. SEM analysis to assess the failure mode was evaluated on the representative samples. The normality of the data was assessed using the Shapiro-Wilkinson test. Inferential statistics were done using the Whitney U Test (between the groups). Results: Results of all the test groups (Groups 2-5) had statistically significant differences ( Conclusions: The null hypothesis was rejected. Remineralizing agents enhance the shear bond strength of composite to in-office bleached enamel using the total-etch technique. Regenerate paste (nR5 Technology) showed statistically better results than Curodont Repair paste (p11-4 peptide).

Identifiers

PMID40485965
PMCPMC12142359

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.