ArticleJournal of contemporary brachytherapy2025
Evaluation of risk factors for difficult-to-control pain (VAS score > 3) at two months after late-stage non-small cell lung cancer treatment with iodine-125 radioactive particle implantation combined with chemotherapy.
Article in Journal of contemporary brachytherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to explore the risk factors associated with difficult-to-control pain (visual analog scale [VAS] score > 3) experienced by patients with advanced non-small cell lung cancer (NSCLC) assessed at two months after receiving iodine-125 ( Material and methods: A total of 87 patients diagnosed with advanced NSCLC were included in the study, all of whom underwent treatment using Results: The results indicated that minimal pleural distance, smoking history, and pleural effusion were independent risk factors influencing the control of pain shown in VAS scores. Moreover, a non-linear relationship between minimal pleural distance and difficulty of pain control was observed, indicating that the risk of uncontrolled pain decreases when the minimal pleural distance reaches ≥ 10.84 millimeters. ROC curve analysis demonstrated that the predictive capability of minimal pleural distance was the highest. Conclusions: Minimal pleural distance, smoking history, and pleural effusion are significant factors in predicting the difficulty of pain control in patients with advanced NSCLC receiving
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