Evidence map›Paper›PMID 40485714›Full record

ArticleKidney international reports2025

A Comparison of Hospitalization Outcomes Between Peritoneal Dialysis and Home Hemodialysis Patients by Sex and Race.

George Worthen, Meghan Day, Leah Cahill, Louis-Charles Desbiens, Annie-Claire Nadeau-Fredette, Cindy Feng, Rachel Warren, Emilie Trinh, Jeffrey Perl, Christopher Chan and 2 more

Abstract read
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

George WorthenDepartment of Medicine, Queen Elizabeth II Health Sciences Centre, Nova Scotia Health, Halifax, Nova Scotia, Canada.
Meghan DayDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Leah CahillDepartment of Medicine, Queen Elizabeth II Health Sciences Centre, Nova Scotia Health, Halifax, Nova Scotia, Canada.
Louis-Charles DesbiensDivision of Nephrology, Maisonneuve-Rosemont Hospital and Research Center, Montreal, Quebec, Canada.
Annie-Claire Nadeau-FredetteDivision of Nephrology, Maisonneuve-Rosemont Hospital and Research Center, Montreal, Quebec, Canada.
Cindy FengDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Rachel WarrenDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Emilie TrinhDivision of Nephrology, McGill University Health Center, Montreal, Quebec, Canada.
Jeffrey PerlDivision of Nephrology, St. Michael's Hospital, Toronto, Ontario, Canada.
Christopher ChanDivision of Nephrology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
David ClarkDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Karthik TennankoreDepartment of Medicine, Queen Elizabeth II Health Sciences Centre, Nova Scotia Health, Halifax, Nova Scotia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As interest in home dialysis as an initial dialysis modality grows, it remains unclear how the different home dialysis modalities may impact hospitalization outcomes, or how this relationship may change depending on patient sex and race. Methods: We compared all-cause hospitalization rates and days in hospital between incident peritoneal dialysis (PD, Results: The overall hospitalization rate was 0.82 hospitalization events per patient-year. Compared with those initiated on PD, HHD patients had a lower hospitalization rate (incident rate ratio [IRR] = 0.78, 95% confidence interval [CI] 0.71-0.85), and spent fewer days in hospital (IRR = 0.68, 95% CI: 0.59-0.78). This was more pronounced in more contemporary cohorts and for males. The protective effect of HHD was stronger for Black patients. When hospitalizations were analyzed by cause, the protective effect of HHD was stronger for infection-related admissions, with Black patients seeing the largest benefit. Conclusion: The type of home modality at dialysis initiation is associated with differences in hospitalization outcomes, an association that is stronger in selected racial groups and sexes. While exploratory in nature, our work highlights the importance of further study on the differential impact of PD and HHD on hospitalization outcomes so that patients incident to dialysis may make an informed decision.

Indexed as

home dialysishospitalizationrace

Identifiers

PMID40485714
PMCPMC12142620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.