Evidence map›Paper›PMID 40485562›Full record

ArticleeLife2025

Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in

Pengzhen Dong, Yue Li, Yuying Wang, Qiang Zhao, Tianfeng Lu, Jian Chen, Tianyu Guo, Jun Ma, Bing Yang, Honggang Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Growth hormone regulates the stem cell population in the growth plate.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pengzhen DongSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0009-0009-7124-695X
Yue LiSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Yuying WangSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Qiang ZhaoSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Tianfeng LuDepartment of Developmental Biology and Neuroscience, Washington University in St. Louis, Missouri, Washington DC, United States.
Jian ChenSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Tianyu GuoSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Jun MaCenter for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Bing YangMOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences, Institute, Zhejiang University, Hangzhou, China.
Honggang WuZhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hai HuangSecond Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0003-2331-6238

Funding

National Key Research and Development Program of China 2022YFF0608402National Natural Science Foundation of China 22374128National Natural Science Foundation of China NSFC32000574National Natural Science Foundation of China NSFC32070784National Natural Science Foundation of China NSFC32300699National Natural Science Foundation of China NSFC92168101Postdoctoral Research Foundation of China 2023M733098Zhejiang Association for Science and Technology LQ24C120001
6 · The paper itself

Abstract

Coordinated activation and directional migration of adult stem cells are essential for maintaining tissue homeostasis.

Indexed as

Cell MovementCytokinesDrosophila melanogasterDrosophila ProteinsFat BodyStem CellsTracheaTranscription FactorsAnimalsJanus KinasesSignal TransductionSTAT Transcription FactorsCytokinesDrosophila ProteinsJanus KinasesSTAT Transcription FactorsTranscription FactorsUpd2 protein, Drosophilaadult stem cellscell migrationdevelopmental biologyD. melanogasterinter-organ communicationtrachea

Identifiers

PMID40485562
PMCPMC12148326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.