Evidence map›Paper›PMID 40485434›Full record

ArticleJournal of materials chemistry. B2025

Rhodamine-derived ratiometric fluorescent probes for high-sensitivity detection and real-time imaging of mitochondrial pH and viscosity in HeLa cells and

Subash Pandey, Dilka Liyana Arachchige, Ronald J Schwandt, Sushil K Dwivedi, Ishana Kathuria, Haiying Liu, Rudy L Luck

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Subash PandeyDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.
Dilka Liyana ArachchigeDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.
Ronald J SchwandtDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.
Sushil K DwivediDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.
Ishana KathuriaDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.
Haiying LiuDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.ORCID http://orcid.org/0000-0001-8351-2017
Rudy L LuckDepartment of Chemistry, Michigan Technological University, Houghton, MI 49931, USA. rluck@mtu.edu.ORCID http://orcid.org/0000-0001-5436-1942

Funding

Near-infrared Fluorescent Probes for Sensitive Detection of NADH in Live CellsR15GM146206 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LIU, HAIYING · 2022 to 2024
$588k
Preparative binary pump HPLC system with UV and refractive index detector capabilitiesR15GM152969 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LUCK, RUDY LIN · 2023 to 2024
$547k
NIGMS NIH HHS R15 GM146206NIGMS NIH HHS R15 GM152969
6 · The paper itself

Abstract

The spirolactam on/off switch attached to rhodamine dye is known to be a highly selective and sensitive fluorescent probe, yet few studies have explored extending the π-conjugation system within its skeleton for pH detection in live cells. An extended π-conjugated rhodamine section should enable ratiometric pH detection in the near-infrared region. In this study, we synthesized probes A and B by coupling a rhodamine derivative with 7-nitrobenzofurazan and 7-(diethylamino)-2-oxo-3,8

Indexed as

Fluorescent DyesMitochondriaRhodaminesAnimalsDrosophila melanogasterFluorescence Resonance Energy TransferHeLa CellsHumansHydrogen-Ion ConcentrationMolecular StructureOptical ImagingViscosityFluorescent DyesRhodamines

Identifiers

PMID40485434
PMCPMC12435310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.