Evidence map›Paper›PMID 40485169›Full record

ArticleCell biochemistry and function2025

ZIP14 Deletion Disrupts Divalent Metal Homeostasis in Mouse Cerebrospinal Fluid.

Shannon M McCabe, Ningning Zhao

Abstract read
In one paragraph

Article in Cell biochemistry and function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shannon M McCabeSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, Arizona, USA.
Ningning ZhaoSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, Arizona, USA.ORCID https://orcid.org/0000-0002-3780-9095

Funding

Molecular mechanism underlying the regulation of manganese homeostasisR01DK123113 · NIDDK · UNIVERSITY OF ARIZONA · PI ZHAO, NINGNING · 2020 to 2024
$1.8M
NIDDK NIH HHS R01 DK123113The work was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Office of Dietary Supplements (ODS) of the National Institutes of Health (NIH) (R01DK123113).
6 · The paper itself

Abstract

ZIP14 is a member of the SLC39A (ZIP) family of metal transporters, primarily facilitating the cellular influx of divalent metals including manganese (Mn), zinc (Zn), and iron (Fe). Previous studies have demonstrated that Zip14 knockout (Zip14

Indexed as

Cation Transport ProteinsGene DeletionHomeostasisAnimalsCalciumFemaleIronMaleManganeseMiceMice, Inbred C57BLMice, KnockoutZincCalciumCation Transport ProteinsIronManganeseSLC39A14 protein, mouseZincbraincerebrospinal fluid (CSF)ironmanganesenutrientzincZIP14

Identifiers

PMID40485169
PMCPMC12175151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.