Evidence map›Paper›PMID 40485149›Full record

ArticleNeurogastroenterology and motility2025

Long-Term Clinical and Physiological Outcomes in Patients Treated Non-Surgically for Anorectal Malformations.

Venla E C den Hollander, Steffie Gerritsen, Monika Trzpis, Paul M A Broens

Abstract read
In one paragraph

Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Venla E C den HollanderDepartment of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-9581-0900
Steffie GerritsenDepartment of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Monika TrzpisDepartment of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Paul M A BroensDepartment of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aim to investigate the long-term clinical anorectal outcomes and anorectal physiology in patients treated non-surgically for minor types of anorectal malformations (ARM).

methodsWe retrospectively included 79 non-surgically treated patients born with minor types of ARM. We investigated constipation and fecal incontinence according to the Rome IV criteria, as well as anorectal physiology using anorectal manometry. KEY

resultsOf all patients, 60% reported no constipation and no fecal incontinence, 38% experienced constipation, and 2% had fecal incontinence. All patients could contract the external anal sphincter and the puborectal muscle, both voluntarily and involuntarily, and 94% possessed a functional internal anal sphincter. The mean anal sensibility was 2.5 mA. CONCLUSIONS AND INFERENCES: The long-term anorectal outcomes of non-surgically treated patients diagnosed with minor types of ARM seem optimal. Most of these patients experience no constipation and fecal incontinence; some experience constipation and relatively seldom fecal incontinence. Furthermore, most patients possess all the known fecal continence mechanisms. This study demonstrates that patients with minor ARM who received non-surgical treatment can achieve optimal anorectal function outcomes.

Indexed as

Anal CanalAnorectal MalformationsFecal IncontinenceRectumAdolescentAdultChildChild, PreschoolConstipationFemaleHumansMaleManometryRetrospective StudiesTreatment OutcomeYoung Adultanal canalanorectal malformationsanorectal manometryconstipationfecal continence

Identifiers

PMID40485149
PMCPMC12623284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.