ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025
Electrocardiographic R Wave Peak Time: Correlation With the Severity of Coronary Artery Disease and Prognosis in Patients With Acute Coronary Syndrome.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- R-Wave Peak Time and Impaired Coronary Collateral Circulation in Chronic Total Occlusion.Journal of clinical medicine · 2026Article
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6 authors.
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Abstract
backgroundElectrocardiographic parameters have emerged as valuable noninvasive markers for risk stratification in acute coronary syndrome (ACS).
aimsThis study aimed to evaluate the correlation between R wave peak time (RWPT) and coronary artery disease (CAD) severity, and to assess its prognostic value for in-hospital major adverse cardiac events (MACE) in ACS patients.
methodsWe retrospectively analyzed 183 ACS patients who underwent coronary angiography at our hospital between January 2020 and December 2023. RWPT, QRS duration, and P wave peak time were measured from admission electrocardiograms. CAD severity was quantified using the Gensini score, with patients classified into mild (score < 25, n = 81) and moderate-severe (score ≥ 25, n = 102) groups. In-hospital MACE was systematically recorded during hospitalization.
resultsRWPT demonstrated a strong positive correlation with the Gensini score (r = 0.7, p < 0.001). Patients with moderate-severe CAD exhibited significantly prolonged RWPT compared to those with mild disease (43.2 ± 6.3 vs. 36.8 ± 5.3 ms, p < 0.001). Similarly, patients who experienced MACE had significantly longer RWPT than those without complications (44.7 ± 6.2 vs. 37.1 ± 5.5 ms, p < 0.001). In-hospital MACE occurred in 25 patients (13.7%). Multivariate logistic regression analysis identified both RWPT (OR: 1.10, 95% CI: 1.05-1.15, p < 0.001) and diabetes mellitus (OR: 3.02, 95% CI: 1.16-7.93, p = 0.024) as independent risk factors of in-hospital MACE.
conclusionRWPT measured on admission electrocardiograms correlates significantly with CAD severity and independently predicts in-hospital MACE in ACS patients. As a simple, readily available parameter, RWPT may enhance risk stratification in ACS, particularly in resource-limited settings where advanced imaging or biomarker testing access is constrained.
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