ArticleBMC emergency medicine2025
Co-design of a Mobile Stroke Unit pathway highlights uncertainties and trade-offs for viable system-wide implementation in the English and Welsh NHS.
Article in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health Economic & Implementation Determinants of Prehospital Stroke Triage Tools: A Systematic Review.Journal of evaluation in clinical practice · 2026Pooled it
- Modelling the potential clinical benefit of mobile stroke units in England.BMC emergency medicine · 2025Article
- Usability testing a web application to support evidence-based commissioning decisions for implementing mobile stroke units.NPJ digital medicine · 2025Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
backgroundMobile stroke units (MSUs) are specialist ambulances equipped with scanning and point of care testing that can identify patients eligible for intravenous thrombolysis - medication to dissolve a clot used in ischaemic strokes - and provide this on location. While benefits of MSUs have been demonstrated, this is context dependent. Routine use of MSUs across the English and Welsh National Health Service (NHS) has not yet been considered, and as such no pathway for their operation exists. This study aimed to co-design a viable pathway, detailing dispatch, staffing and treatment decisions, for MSUs within the NHS context.
methodsThe study used interdisciplinary co-design alongside Nominal Group Technique (NGT) to generate consensus. Participants were recruited using a combination of purposive, opportunistic and snowball sampling. Data collection took place in online workshops, across three rounds, with supplemental interviews conducted where required. Data were analysed as an ongoing process, with participants checking interpretations after each round, and then further analysed deductively to identify key uncertainties following all the rounds. Consensus threshold for the NGT was set a priori at ≥ 80%.
resultsAn MSU pathway that reached consensus for being viable within the NHS was developed with consideration for current systems and pressures. Key uncertainties were identified such as where to base the MSU. We also identified where participants had to make trade-offs in the co-designed pathway, such as staffing considerations. Together, the uncertainties and trade-offs represent challenges to MSU implementation and are presented alongside the process to reach the finalised pathway. Future developments which may have implications for the implementation of MSUs were also explored.
conclusionsThe co-designed MSU pathway provides a foundation for MSU implementation in the English and Welsh NHS and can be subjected to local and regional modifications required for implementation. However, optimal implementation is likely hindered by several uncertainties and trade-offs, including the geographical base of the MSU and staffing, that represent challenges to implementation of MSUs at scale. Future developments in acute stroke care may help to mitigate these challenges, such as developments in artificial intelligence to read scans and improved access to telemedicine. CLINICAL TRIAL NUMBER: Not applicable.
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